CS228912B2 - Method of preparing isosorbid-5-nitrate - Google Patents

Method of preparing isosorbid-5-nitrate Download PDF

Info

Publication number
CS228912B2
CS228912B2 CS82506A CS50682A CS228912B2 CS 228912 B2 CS228912 B2 CS 228912B2 CS 82506 A CS82506 A CS 82506A CS 50682 A CS50682 A CS 50682A CS 228912 B2 CS228912 B2 CS 228912B2
Authority
CS
Czechoslovakia
Prior art keywords
acylate
isosorbide
isosorbit
nitrate
mixture
Prior art date
Application number
CS82506A
Other languages
Czech (cs)
English (en)
Inventor
Peter Stoss
Original Assignee
Mack Chem Pharm
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mack Chem Pharm filed Critical Mack Chem Pharm
Publication of CS228912B2 publication Critical patent/CS228912B2/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CS82506A 1981-01-29 1982-01-25 Method of preparing isosorbid-5-nitrate CS228912B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19813102947 DE3102947A1 (de) 1981-01-29 1981-01-29 Verfahren zur herstellung von isosorbid-5-nitrat

Publications (1)

Publication Number Publication Date
CS228912B2 true CS228912B2 (en) 1984-05-14

Family

ID=6123585

Family Applications (1)

Application Number Title Priority Date Filing Date
CS82506A CS228912B2 (en) 1981-01-29 1982-01-25 Method of preparing isosorbid-5-nitrate

Country Status (11)

Country Link
US (1) US4371703A (en])
EP (1) EP0057847B1 (en])
JP (1) JPS57144288A (en])
AT (1) ATE8142T1 (en])
CS (1) CS228912B2 (en])
DD (1) DD202030A5 (en])
DE (2) DE3102947A1 (en])
DK (1) DK154562C (en])
GR (1) GR75145B (en])
IE (1) IE52409B1 (en])
PL (1) PL130559B1 (en])

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3117612A1 (de) * 1981-05-05 1982-11-25 Cassella Ag, 6000 Frankfurt Verfahren zur herstellung von isosorbid-5-nitrat
DE3124410A1 (de) * 1981-06-22 1983-01-05 Heinrich Mack Nachf., 7918 Illertissen Verfahren zur herstellung von isosorbid-2-nitrat
JPS5818385A (ja) * 1981-07-27 1983-02-02 Toa Eiyou Kagaku Kogyo Kk イソソルビド−５−ニトレ−トの製造法
US5538891A (en) * 1991-09-02 1996-07-23 Boehringer Mannheim Gmbh Process for enzymatic production of isomerically pure isosorbide-2 and 5-monoesters and their conversion to isosorbide-2 and -5 nitrate
DE4129093A1 (de) * 1991-09-02 1993-03-04 Schneider Manfred Prof Dr Verfahren zur enzymatischen herstellung isomerenreiner isosorbid-2- und -5-monoester sowie deren ueberfuehrung in isosorbid-2- und -5-nitrat
DE4410997A1 (de) * 1994-03-30 1995-10-26 Isis Pharma Gmbh Pharmazeutische Zubereitungen und Arzneistoffe zur Prävention und Behandlung endothelialer Dysfunktionen
EP1046692B1 (de) 1999-04-15 2002-08-07 Consortium für elektrochemische Industrie GmbH Thermostabile Pigmente, Filme und Effektbeschichtungen sowie Mischungen zu deren Herstellung
FR2810040B1 (fr) * 2000-06-09 2004-04-09 Roquette Freres Procede de purification d'une composition contenant au moins un produit de deshydratation interne d'un sucre hydrogene
FR2832407B1 (fr) * 2001-11-20 2005-07-01 Roquette Freres Procede de preparation d'une composition contenant au moins un produit de deshydratation interne d'un sucre hydrogene
ES2258365B1 (es) * 2003-10-03 2007-12-01 Lacer, S.A. Derivados de disulfuro, sulfuro, sulfoxido y sulfona de azucares ciclicos y sus usos.
DE102008050597A1 (de) 2008-10-09 2010-04-15 Actavis Deutschland Gmbh & Co. Kg Pharmazeutische Zubereitungen zur Anwendung in einem Verfahren zur therapeutischen Behandlung von Hörsturz
JP6457522B2 (ja) * 2013-12-19 2019-01-23 アーチャー−ダニエルズ−ミッドランド カンパニー グリコールのアシル化における向上した位置選択性
KR102107274B1 (ko) * 2014-04-10 2020-05-06 아처 다니엘 미드랜드 캄파니 산 촉매의 혼합 조합을 이용한 당 알코올의 탈수
CN106146527A (zh) * 2015-04-24 2016-11-23 中国科学院大连化学物理研究所 一种二羧酸异山梨醇酯增塑剂的制备方法
CN113105470A (zh) * 2021-03-15 2021-07-13 海南通用康力制药有限公司 单硝酸异山梨酯的合成方法及应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4065488A (en) 1977-02-24 1977-12-27 American Home Products Corporation Process for preparing 1,4:3,6-dianhydro-D-glucitol 2-nitrate
DE2903927C2 (de) 1979-02-02 1981-03-12 Sanol Schwarz-Monheim Gmbh, 4019 Monheim Verfahren zur selektiven Herstellung von Isosorbid-5-nitrat
DE3028873C2 (de) * 1980-07-30 1983-10-27 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren zur Herstellung von 1,4 zu 3,6-Dianhydro-D-glucit-5-nitrat (Isosorbid-5-nitrat)

Also Published As

Publication number Publication date
EP0057847B1 (de) 1984-06-27
IE52409B1 (en) 1987-10-14
DE3102947A1 (de) 1982-09-02
US4371703A (en) 1983-02-01
IE820187L (en) 1982-07-29
DK154562C (da) 1989-05-01
JPH031312B2 (en]) 1991-01-10
EP0057847A1 (de) 1982-08-18
JPS57144288A (en) 1982-09-06
ATE8142T1 (de) 1984-07-15
PL235019A1 (en]) 1982-08-30
DD202030A5 (de) 1983-08-24
DE3260280D1 (en) 1984-08-02
DK154562B (da) 1988-11-28
PL130559B1 (en) 1984-08-31
GR75145B (en]) 1984-07-13
DK38282A (da) 1982-07-30

Similar Documents

Publication Publication Date Title
FI71942C (fi) Foerfarande foer framstaellning av 4'- demetyl-epipodofyllotoxin- -d-etyliden-glukosid och mellanprodukt som anvaends vid foerfarandet.
CS228912B2 (en) Method of preparing isosorbid-5-nitrate
SU577982A3 (ru) Способ получени 2-тетрагидрофурфурил6,7-бензоморфанов или их солей
KR0163022B1 (ko) 13,14-디하이드로-15(r)-17-페닐-18,19,20-트리노-pgf2알파 에스테르의 제조방법
KR20000068437A (ko) 2-아미노말론산유도체와 2-아미노-1,3-프로판디올유도체의 제조방법, 그리고 이들 유도체를 제조하기 위한 중간체
JP4667691B2 (ja) ナプロキセンのニトロキシアルキルエステルの製造法
US4297286A (en) Process for selectively producing isosorbide-5-nitrate
US20080221340A1 (en) Process for the Production of Nebivolol
EP3854800B1 (en) High-yield preparation method for novel vascular leakage blocker
JPH0129191B2 (en])
Glarner et al. The photohydration of N-glycosylpyridinium salts and of related pyridinium N, O-acetals
EP0243646B1 (en) A process for the preparation of forskolin from 9-deoxy-forskolin and intermediates used therein
JPS6317077B2 (en])
US4464534A (en) Process for the preparation of vincaminic acid esters
KR102587674B1 (ko) 트레프로스티닐의 제조방법
SU1435153A3 (ru) Способ получени сложного этилового эфира аповинкаминовой кислоты
KR100403143B1 (ko) 1-브로모에틸 아세테이트의 제조방법
KR860000767B1 (ko) 니자티딘의 합성법
SU922108A1 (ru) Способ получени производных 6-метил-8 @ -гидразинометилэрголина или их солей
EP4034540B1 (en) Method of making and/or isolating isoidide, comprising selective esterification of a mixture of dianhydrohexitol isomers
WO2022195288A1 (en) Process for the preparation of an n-acylethanolamide derivative
SU1348340A1 (ru) Способ получени 2-этил-1,6-диоксаспиро (4,4)нонана
SU1179921A3 (ru) Способ получени сложных этиловых эфиров 1-метил-или 1,4-диметил-1 @ -пиррол-2-уксусной кислоты
CN114105862A (zh) 盐酸多奈哌齐杂质及其制备方法
KR890004131B1 (ko) 3-하이드록시-5-메틸 이속사졸의 제조방법